| 摘要: | 許多營養素與多酚類具有免疫調節作用，有可能改變對SARS-CoV-2感染、症狀進展、疾病嚴重的可能性和存活率。本綜合回顧主要針對相關慢性疾病、營養性問題、營養成分與多酚類及其對SARS-CoV-2的影響作綜論分析。相關慢性疾病包括：超重（over weight）、肥胖（obesity）和糖尿病（diabetes mellitus）；營養性問題包括：蛋白質－能量營養不良（protein-energy malnutrition）和貧血（anemia）；營養成分包括：維生素C、D和E；多不飽和脂肪酸、鐵、硒、鋅與抗氧化劑（antioxidants）等；多酚類（polyphenols）主要包括：黃酮類（flavonoids）如：黄酮醇（flavonols）、黃烷酮（flavanone）、花青素（anthocyanidins）與非黃酮類（non-flavonoids）如：單寧（tannins）、酚酸（phenolic acids）、芪（stilbenes）、糖苷（glucosides）等。其中以具有特定結構的聚丙烯酸酯化花青素（polyacrylate-containing anthocyanins）、可水解單寧，可用作有效的抗SARS-CoV-2天然成分。而目前關於天然植物功效的實驗研究集中在多酚對SARS-CoV-2治療的潛力。
Many nutrients and polyphenols have immunomodulatory effects, which may change the possibility of SARS-CoV-2 infection, symptom progression, the severity of disease, and survival rate. This review mainly focuses on related chronic diseases, nutritional problems, nutrient component and polyphenols, and their effects on SARS-CoV-2. Related chronic diseases include: overweight, obesity, and diabetes mellitus; nutritional problems include: protein-energy malnutrition and anemia; nutrient component include: vitamin C, D, and E; polyunsaturated fatty acids, iron, selenium, zinc, and antioxidants, etc.; polyphenols mainly include: flavonoids such as flavonols, flavanones, anthocyanidins, and non-flavonoids such as tannins, phenolic acids, stilbenes, glucosides, etc. Among them, polyacrylate-containing anthocyanins and hydrolyzable tannins with specific structures can be used as effective anti-SARS-CoV-2 natural ingredients. The current experimental research on the efficacy of natural plants focuses on the therapeutic potential of polyphenols against SARS-CoV-2. |
