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請使用永久網址來引用或連結此文件:
https://irlib.pccu.edu.tw/handle/987654321/53191
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| 題名: | Comparison of Immune-Related Gene Expression in Two Chicken Breeds Following Infectious Bronchitis Virus Vaccination |
| 作者: | Chuwatthanakhajorn, Schwann
Chang, Chi-Sheng
Ganapathy, Kannan
Tang, Pin-Chi
Chen, Chih-Feng
張啟聖 |
| 貢獻者: | Department of Animal Science |
| 關鍵詞: | differentially expressed gene
immune response traits
infectious bronchitis virus vaccination
RNA-seq
spleen transcriptomic |
| 日期: | 2023-05 |
| 上傳時間: | 2024-03-12 15:35:01 (UTC+8) |
| 出版者: | Multidisciplinary Digital Publishing Institute |
| 摘要: | This study aims to identify the immune-related genes and the corresponding biological pathways following infectious bronchitis virus vaccination in Taiwan Country and White Leghorn chicken breeds. Transcriptomic analyses of the spleen of these two breeds were conducted by next-generation sequencing. Compared to White Leghorn chicken, Taiwan Country chicken showed a significantly higher level of anti-infectious bronchitis virus (IBV) antibodies at 14 and 21 days pos vaccination. At 7 days post vaccination, in the Taiwan Country chicken, higher expression of mitogen-activated protein kinase 10, Major histocompatibility complex class 1, and V-set pre-B cell surrogate light chain 3 were found. In contrast, the White Leghorn chicken had a high expression of interleukin 4 induced 1, interleukin 6, and interleukin 22 receptor subunit alpha 2. These findings have highlighted the variations in immune induction between chickens with distinct genetic background and provided biological pathways and specific genes involved in immune responses against live attenuated IBV vaccine. |
| 關聯: | Animals |
| 顯示於類別: | [動物科學系 ] 期刊論文
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