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請使用永久網址來引用或連結此文件:
https://irlib.pccu.edu.tw/handle/987654321/41876
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| 題名: | Impedance measurement system for automatic determination of glycated hemoglobin |
| 作者: | Tsai, SA (Tsai, Shou-Ai)
Tang, JY (Tang, Jing-Yau)
Wang, MH (Wang, Min-Haw)
Jang, LS (Jang, Ling-Sheng) |
| 貢獻者: | 電機工程系 |
| 關鍵詞: | SELF-ASSEMBLED MONOLAYERS
BIOMEDICAL APPLICATIONS
HBA(1C)
SPECTROSCOPY
ELECTRODES
STABILITY
BIOSENSOR
PLANAR
ARRAYS |
| 日期: | 2018-06 |
| 上傳時間: | 2019-01-17 14:46:26 (UTC+8) |
| 摘要: | In this study, an automatic glycated hemoglobin (HbA1c) impedance measurement system (AHMS) is developed for the detection of HbA(1c). The proposed device removes some of the drawbacks of common instruments for HbA(1c) detection (i.e., large, expensive, difficult to operate) by detecting the ratio of HbA(1c) to Hb. The method is label-free and requires only a small sample volume; no additional reagents are required. The manpower consumption and bulk of the instrument are also reduced. The method provides a simple way to analyze impedance deviation and effectively reduces the effort required by the operator. The ratios of HbA(1c) to Hb (4%-7%) are well distinguished, and the experiment is used to build a database for AHMS. To check the reliability of the proposed system, a sample test using three different ratios of HbA(1c) is applied in this study. The sample test uses HbA(1c) to Hb ratios of 4.7%, 5.6%, and 6.8%, and the determined experimental values are 4.93%, 5.8%, and 6.83%, respectively. The sample test has an accuracy of approximately 96.99%. Based on these results, the proposed system for detecting HbA(1c) through protein coverage is both effective and feasible. Published by AIP Publishing. |
| 顯示於類別: | [電機工程系] 期刊論文
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