文化大學機構典藏 CCUR:Item 987654321/41876
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://irlib.pccu.edu.tw/handle/987654321/41876


    题名: Impedance measurement system for automatic determination of glycated hemoglobin
    作者: Tsai, SA (Tsai, Shou-Ai)
    Tang, JY (Tang, Jing-Yau)
    Wang, MH (Wang, Min-Haw)
    Jang, LS (Jang, Ling-Sheng)
    贡献者: 電機工程系
    关键词: SELF-ASSEMBLED MONOLAYERS
    BIOMEDICAL APPLICATIONS
    HBA(1C)
    SPECTROSCOPY
    ELECTRODES
    STABILITY
    BIOSENSOR
    PLANAR
    ARRAYS
    日期: 2018-06
    上传时间: 2019-01-17 14:46:26 (UTC+8)
    摘要: In this study, an automatic glycated hemoglobin (HbA1c) impedance measurement system (AHMS) is developed for the detection of HbA(1c). The proposed device removes some of the drawbacks of common instruments for HbA(1c) detection (i.e., large, expensive, difficult to operate) by detecting the ratio of HbA(1c) to Hb. The method is label-free and requires only a small sample volume; no additional reagents are required. The manpower consumption and bulk of the instrument are also reduced. The method provides a simple way to analyze impedance deviation and effectively reduces the effort required by the operator. The ratios of HbA(1c) to Hb (4%-7%) are well distinguished, and the experiment is used to build a database for AHMS. To check the reliability of the proposed system, a sample test using three different ratios of HbA(1c) is applied in this study. The sample test uses HbA(1c) to Hb ratios of 4.7%, 5.6%, and 6.8%, and the determined experimental values are 4.93%, 5.8%, and 6.83%, respectively. The sample test has an accuracy of approximately 96.99%. Based on these results, the proposed system for detecting HbA(1c) through protein coverage is both effective and feasible. Published by AIP Publishing.
    显示于类别:[電機工程系] 期刊論文

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