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題名: | Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer |
作者: | Hsieh, CH (Hsieh, Chen-Hsi) Kuo, YS (Kuo, Ying-Shiung) Liao, LJ (Liao, Li-Jen) Hu, KY (Hu, Kawang-Yu) Lin, SC (Lin, Shih-Chiang) Wu, LJ (Wu, Le-Jung) Lin, YC (Lin, Yu-Chin) Chen, YJ (Chen, Yu-Jen) Wang, LY (Wang, Li-Ying) Hsieh, YP (Hsieh, Yen-Ping) Lin, SL (Lin, Shoei Long) Chen, CY (Chen, Chun-Yi) Chen, CA (Chen, Chien-An) Shueng, PW (Shueng, Pei-Wei) |
貢獻者: | Grad Inst Sport Coaching Sci |
關鍵詞: | SQUAMOUS-CELL CARCINOMA PROSPECTIVE RANDOMIZED TRIAL NECK-CANCER CONFORMAL RADIOTHERAPY RADIATION-THERAPY TARGET VOLUMES ADVANCED HEAD IRRADIATION DELINEATION EXPERIENCE |
日期: | 2011-01-27 |
上傳時間: | 2013-01-30 13:37:19 (UTC+8) |
摘要: | Background: The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.
Methods: From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.
Results: The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation <= 6 wk, and the overall treatment time of radiation <= 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.
Conclusions: HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings. |
關聯: | BMC CANCER 卷: 11 文獻號碼: 37 |
顯示於類別: | [運動教練研究所] 期刊論文
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