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    题名: Image-guided intensity modulated radiotherapy with helical tomotherapy for postoperative treatment of high-risk oral cavity cancer
    作者: Hsieh, CH (Hsieh, Chen-Hsi)
    Kuo, YS (Kuo, Ying-Shiung)
    Liao, LJ (Liao, Li-Jen)
    Hu, KY (Hu, Kawang-Yu)
    Lin, SC (Lin, Shih-Chiang)
    Wu, LJ (Wu, Le-Jung)
    Lin, YC (Lin, Yu-Chin)
    Chen, YJ (Chen, Yu-Jen)
    Wang, LY (Wang, Li-Ying)
    Hsieh, YP (Hsieh, Yen-Ping)
    Lin, SL (Lin, Shoei Long)
    Chen, CY (Chen, Chun-Yi)
    Chen, CA (Chen, Chien-An)
    Shueng, PW (Shueng, Pei-Wei)
    贡献者: Grad Inst Sport Coaching Sci
    关键词: SQUAMOUS-CELL CARCINOMA
    PROSPECTIVE RANDOMIZED TRIAL
    NECK-CANCER
    CONFORMAL RADIOTHERAPY
    RADIATION-THERAPY
    TARGET VOLUMES
    ADVANCED HEAD
    IRRADIATION
    DELINEATION
    EXPERIENCE
    日期: 2011-01-27
    上传时间: 2013-01-30 13:37:19 (UTC+8)
    摘要: Background: The aim of this study was to assess the treatment results and toxicity profiles of helical tomotherapy (HT) for postoperative high-risk oral cavity cancer.

    Methods: From December 6, 2006 through October 9, 2009, 19 postoperative high-risk oral cavity cancer patients were enrolled. All of the patients received HT with (84%) or without (16%) chemotherapy.

    Results: The median follow-up time was 17 months. The 2-year overall survival, disease-free survival, locoregional control, and distant metastasis-free rates were 94%, 84%, 92%, and 94%, respectively. The package of overall treatment time > 13 wk, the interval between surgery and radiation <= 6 wk, and the overall treatment time of radiation <= 7 wk was 21%, 84%, and 79%, respectively. The percentage of grade 3 mucositis, dermatitis, and leucopenia was 42%, 5% and 5%, respectively.

    Conclusions: HT achieved encouraging clinical outcomes for postoperative high-risk oral cavity cancer patients with high compliance. A long-term follow-up study is needed to confirm these preliminary findings.
    關聯: BMC CANCER 卷: 11 文獻號碼: 37
    显示于类别:[運動教練研究所] 期刊論文

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