The idea of using unmanned devices to drop off items at front doors or backyards is becoming more popular and it has been tested by private companies around the world. As e-commerce continues to grow; unmanned aerial vehicles or drones have the possibility to reduce the time, cost and energy for deliveries, becoming an alternative for companies to reach their customers faster. The food industry is considering this new way of delivering food, and companies around the world are already testing this service, but to be a viable resource some research about the potential aspects to consider at the time of implementing is needed. This study attempts to develop a comprehensive research framework to identify the key success factors for the adoption of a drone-based food delivery service that can give ground for its implementation. The empirical result illustrated that right permissions & regulations, public safety, environmental impact, privacy and drone noise are the most important aspects to consider for using drones for food delivery.