兩極化訓練的有氧適應路徑與誘發內皮細胞生長因子表現量、血管生成素、心血管系統適應性及有氧運動表現之效果

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Title:	兩極化訓練的有氧適應路徑與誘發內皮細胞生長因子表現量、血管生成素、心血管系統適應性及有氧運動表現之效果 Effects of Polarized Training on Aerobic Adaptation Pathway and the Induction of Vascular Endothelial Growth Factor Expression, Angiopoietin, Cardiovascular System Adaptation and Aerobic Exercise Performance
Authors:	吳慧君
Contributors:	體育學系
Keywords:	乳酸閾值換氣閾值訓練強度分佈血流動力學心肺適能
Date:	2019-2020
Issue Date:	2019-10-31 14:46:22 (UTC+8)
Abstract:	研究目的：探討健康成人從事高量低強度 (HVT)、高強度間歇訓練 (HIIT) 及兩極化訓練 (POL) 的有氧適應路徑差異，進一步比較週期性 (periodization) 與單次運動設計 (single session design) 的兩極化訓練 (POL-M；POL-SSD)，誘發有氧適應能力、內皮細胞生長因子表現量、血管生成素、心血管系統適應性及有氧運動表現之效果。研究方法：第一年計畫欲招募健康成人共 64 名，隨機分配至CG、HVT、HIIT 及 POL，每組各 16 名。隨後進行 8 週的運動介入，並於介入前，以及第 1、4 及 9 週最後一次訓練前與後檢測有氧適應路徑指標的急性反應。另外，第 0、5及 10 週檢測有氧適應路徑長期適應性與有氧運動能力表現。第二年計畫欲招募健康成人 40 名，隨機分配至週期性與單次運動 POL 設計 (POL-M；POL-SSD)，每組各 20 名。隨後進行 8 週的運動介入，並於介入前，以及第 1、4 及 9 週最後一次訓練前與後檢測有氧適應能力、內皮細胞生長因子表現量、血管生成素、心血管系統適應性指標的急性反應。另外，第 0、5 及 10 週檢測上述長期訓練適應狀態與有氧運動能力表現。所得資料以混合設計二因子變異數分析檢定不同實驗處理與時間點的差異。以皮爾森績差相關與多元線性迴歸檢驗各項指標間相關性，以及釐清有氧適應途徑和運動表現的影響。預期結果：瞭解是否兩極化訓練有較佳的有氧能力的刺激與生理適應能力，能更有效提升有氧運動表現；相較 POL-SSD，POL-M 是否更能改善整體生理適應能力，進而提升有氧運動能力表現。 Purpose: To compare the differences between high-volume low-intensity (HVT), high intensity interval training (HIIT) and polarized training (POL) in aerobic adaptation pathways, and differences between microcycle and single session design (POL-M; POL-SSD) in polarized training. Further, examining the induction effect of POL on aerobic adaptation capacity, vascular endothelial growth factor expression, adaptation, cardiovascular system adaptability, and aerobic performance in healthy adults. Methods: The first-year project will recruit 64 healthy adults that randomly assigned to CG, HVT, HIIT, and POL with 16 subjects of each. An 8-week exercise intervention is requested. The aerobic adaptation pathway indicators of acute response will be measured at the before and after of last training in week 1, 4, and 9. In addition, the long-term training adaptation and aerobic exercise performance will be evaluated in week 0, 5, and 10. The second-year project will recruit 40 healthy adults that randomly assigned to POL-M and POL-SSD, with 20 subjects of each. An 8-week exercise intervention is also requested. The acute response indicators of aerobic adaptation capacity, vascular endothelial growth factor expression, adaptation, cardiovascular system, and aerobic exercise performance will be evaluated at the before and after of last training in week 1, 4, and 9. In addition, the above parameters were also tested at 0, 5, and 10 weeks. Data will be analyzed by mixed design two-way ANOVA to examine the differences between groups and time points. The pearson's-correlation coefficient will be used to identify the relationship between variables. The multiple stepwise regression analysis will be used to clarify the aerobic adaptation pathway and the training impact on aerobic performance. Expected results: Polarized training reveals a better aerobic stimulation and physiological adaptability, and more effective in improving aerobic performance. Compare to POL-SSD, POL-M has better improvements on overall physiological adaptation ability and aerobic exercise performance.
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