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https://irlib.pccu.edu.tw/handle/987654321/41874
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| 題名: | Microfluidics-based hairpin resonator biosensor for biological cell detection |
| 作者: | Liu, CF (Liu, Chia-Feng)
Wang, MH (Wang, Min-Haw)
Jang, LS (Jang, Ling-Sheng) |
| 貢獻者: | 電機工程系 |
| 關鍵詞: | DIELECTRIC-SPECTROSCOPY
IMPEDANCE SPECTROSCOPY
MICROWAVE-FREQUENCIES
WAVE-GUIDE
SENSOR
TISSUE
LINE
GHZ |
| 日期: | 2018-06-15 |
| 上傳時間: | 2019-01-17 14:35:10 (UTC+8) |
| 摘要: | In this work, a microwave hairpin resonator was used for the detection of biological cells fabricated and integrated with microfluidics. The biosensor was a microfluidic device constructed from polydimethylsiloxane (PDMS) and negative photoresist (SU-8) using micro-electro-mechanical-system(MEMS) technology to measure and characterize biological cells in a liquid medium. A biosensor witha high-Q dielectric resonator allowed the detection of biological cells by measuring the scattering parameter (S-parameter) responses at a resonant frequency of 2.17 GHz. Measurements and analyses of Dulbecco's modified Eagle's medium (DMEM) and B16F10 melanoma cells (musmusculus skin melanoma) were then performed to obtain the linear relationship between S-11 responses and the number of cells. A model of coupled resonators in terms of capacitances was then used to analyze the effects of DMEM and the cells. These results demonstrate the potential of hairpin resonator sensors for the analysis of biological cells. (C) 2018 Elsevier B.V. All rights reserved. |
| 顯示於類別: | [電機工程系] 期刊論文
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