| 摘要: | The purpose of this study was to investigate the effect of a 24 hours ultra marathon race on runner's kidney function and kidney damage. Eleven participants were recruited, with mean age of 45.1±8.77 yr, height of 166.8±6.23 cm and weight of 60.6±6.96 kg, in the 2002 International 24h Race IAU Asia 24-Hour Championship. Blood and urine samples were obtained from participants before the event, at the end of the event, after 48 hours, and 9 days to find the changes in kidney function. The results showed that runner's blood urea nitrogen (BUN), creatinine (CRE) and uric acid (UA) in blood increased, especially BUN and CRE, the specific gravity, pH, albuminuria (PRO), occult blood and ketone bodies in urine changed, but urobilinogen (URO), bilirubin (BIL), glucose did not change significantly. According to results, we found kidney damage occurred at the end of race because the decomposition of protein and amino acid and filtration and reabsorprtion of creatine, nitrogenous base, albumin, red blood cell and ketone bodies in kidney were abnormal. But 48 hr after the race, every parameters in blood reached the normal consistence range and almost reactions in urine became negative. 9 days after the race, all of the parameters in blood and reactions in urine recovered to original level before the race. We found the runner's kidney working normally again 48 hr after the race and 9 days after the race, there was no difference of kidney function between now and before the race. According the results conclude that 24 hours after ultra marathon race, the runners got kidney damage impermanently, 48 hr after race, they could recover to original lever before the race. |
