本文採用濕法紡絲技術製備可吸收抗菌海藻纖維。考察紡絲液濃度、凝固浴濃度和溫度、牽伸比對纖維形貌和力學性能的影響；研究纖維在去離子水、模擬傷口滲出液和PBS緩衝液中的吸液性能及抗菌活性。結果表明，紡絲液濃度為3.5%，凝固浴濃度為3.5%、溫度為30℃，牽伸比為1.2時，纖維形態和力學性能較好。所得纖維對去離子水、模擬滲出液和PBS緩衝液的吸液量分別為1.4、10.9、25.2 g/g；對E.coli和S.aureus的抗菌率分別為76.5%和60.5%，具有優良的吸液能力和抗菌活性。
In this study, absorbent and antibacterial alginate fibers were successfully prepared by wet spinning technique. The effects of process parameters including dope concentration, coagulation bath concentration and temperature, and post-draft ratio on morphologies and mechanical properties of alginate fibers were investigated. Moreover, the absorbency and the antibacterial activity of the resultant alginate fibers were performed in vitro. The results showed alginate fibers with excellent microstructure and mechanical properties were obtained when 3.5% of alginate solution was extruded into 3.5% CaCl2 coagulation solution at 30 °C with drawing ratio of 1.2. The adsorption capacities of the resultant alginate fiber in deionized water, simulated wound exudate and PBS buffer were 1.4, 10.9, 25.2 g/g, respectively. In addition, the alginate fibers exhibited excellent antibacterial activities against E.coli and S.aureus with antibacterial rate of 76.5% and 60.5%, respectively.
