文化大學機構典藏 CCUR:Item 987654321/35700
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 46962/50828 (92%)
造访人次 : 12468203      在线人数 : 790
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻
    主页登入上传说明关于CCUR管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://irlib.pccu.edu.tw/handle/987654321/35700


    题名: 木鼈子皂苷類萃取及其毒性測試
    Studies on Chemical Constituents and Activities of Momordica cochinchinensis
    作者: 陳彥丞
    贡献者: 生物科技研究所
    关键词: 木鼈子
    葫蘆科
    皂苷
    日期: 2017
    上传时间: 2017-03-29 13:07:17 (UTC+8)
    摘要: 木鼈子(Momordica cochinchinensis)為多年生蔓性草質藤本植物,為葫蘆科(Cucurbitaceae),苦瓜屬(Momordica)的植物。中藥木鼈子具有消腫、散熱、止痛等功效,但有關木鼈子藥理學研究的文獻較少,尤其是有關木鼈子主要活性成分的製備。目前的臨床應用已肯定了中藥木鼈子具有清熱抗癌保肝等功效,然而根據先前的研究,木鼈子中的主要化學成分-皂苷是造成上述治療功效的主要原因。本研究計畫以木鼈子葉95%及50%乙醇的萃取物,針對皂苷的活性成分利用一系列色層分析方法並配合生物活性導向篩選(Bioactive-guilded fractionation)進行分離與純化,看是否能分離出新的化合物並檢驗其生物活性作用,於將木鼈子進行更進一步的利用、中醫藥現代化、以及新藥的研發都具有重要意義。
    Momordica cochinchinensis is a perennial herbaceous trailing vine, Cucurbitaceae, and Momordica genus plants. Momordica cochinchinensis as Traditional Chinese medicine has functional effects, such as swelling reduction, heat dissipation, pain relief and so on. However, there’re still less pharmacological research literatures about the preparation of main active ingredient of Momordica cochinchinensis. The clinical application has affirmed currently about effects of Momordica cochinchinensis on anti-cancer and anti-inflammation. According to previous studies, the main chemical ingredient of Momordica cochinchinensis, saponin, has been found to be the primary ingredient of the treatment efficacy. In this study, we used leaves of Momordica cochinchinensis that extracted with 95% and 50% ethanol and by a series of chromatography and bioassay-directed fractionation to separate the ingredients. We’ll then use these ingredients to test their biological activities for exploring the further use of Momordica cochinchinensis, modernization of Traditional Chinese medicine and development of new drugs.
    显示于类别:[生物科技研究所 ] 博碩士論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML304检视/开启


    在CCUR中所有的数据项都受到原著作权保护.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈