| 摘要: | 本研究利用液中硬化包覆法製備海藻酸鈉微膠囊，以海藻酸鈉為殼材樟腦油為芯材，藉由針筒將殼材和芯材滴入氣化鈣溶液中使殼材硬化形成微膠囊。藉由改變膜材濃度與膜材含量的不同對膠囊包覆率的影響，觀察其成形並測其粒徑，以及改變氣化鈣濃度及添加不同比例之PS緩釋劑對膠囊制放性的影響。實驗結果顯示，膠囊在1.0%海藻酸鈉溶液，膜材及芯材混合比例4:1，及2.0%氯化鈣溶液交鏈20mim有最佳的成形性及93.21%的包覆率。0.5%氣化鈣濃度下交鏈10min會呈因定速度制放，若將氣化鈣濃度提高至1.0%-2.0%時，會在短時間停止制放，甚至形成封閉型膠囊。隨著PS添加比例的上升會促使微膠囊制放時間的拉長，在添加比例為10%時其極限制放時間甚至可達737min。
In this study, calcium alginate microsphere was prepared by an orifice method. The sodium alginate was used as wall material, and camphor essential oil mixed with polystyrene was used as core material, in order to investigate the optimal oil content and release properties. The parameters of concentration of wall material, the concentration of calcium chloride and the added amount of PS were discussed. The results indicated that microcapsulation the optimal oil content was 93.2% at the condition of 1% sodium alginate aqueous solution at the ratio of wall/core as 4:1, 2% of CaCl2. The camphor oil was released as near linear velocity at the conditions of 0.5% CaCl2, but became a closed type with CaCl2 over 1.0%. As PS content increased, the limit release time was better than pure camphor only. The limit release time was 737min as PS content was 10%. |
