文化大學機構典藏 CCUR:Item 987654321/30866
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://irlib.pccu.edu.tw/handle/987654321/30866


    题名: Yeast with bacteriocin from ruminal bacteria enhances glucose utilization, reduces ectopic fat accumulation, and alters cecal microbiota in dietary-induced obese mice
    作者: Tsai, Yi-Chen
    Wang, Han-Tsung
    Hsu, Jih-Tay
    Li, Yi-Hung
    Chen, Ching-Yi
    贡献者: Dept Anim Sci
    关键词: BROILER-CHICKENS
    ALBUSIN B
    SACCHAROMYCES-CEREVISIAE
    NUTRIENT DIGESTIBILITY
    INTESTINAL-ABSORPTION
    GROWTH-PERFORMANCE
    ANAEROBIC-BACTERIA
    DOSE-RESPONSE
    SUPPLEMENTATION
    METABOLISM
    日期: 2015
    上传时间: 2015-11-03 16:13:05 (UTC+8)
    摘要: Background: This study investigated the effect of yeast with bacteriocin (YB) on the homeostasis of lipid and glucose in diet-induced obese (DIO) mice. Seven-week-old C57BL/6 male mice were fed with a Western diet for 24 weeks to induce obesity. These DIO mice were randomly assigned to 2 groups: obese control (WS) and WYB [0.125 mu g YB per g body weight (BW)]. YB was administered daily to the WYB mice in the last 4 weeks, while an equal volume of normal saline was administered to the WS mice. Results: YB caused a significant reduction in BW, and in plasma levels of total cholesterol and glucose. Less hepatic lipid accumulation and smaller adipocytes were observed in WYB mice. WYB mice had higher lipid catabolism in liver and adipose tissue. Compared with WS mice, WYB mice had higher glycolysis in the liver and muscles. YB suppressed hepatic GLUT5 expression, altered the composition of cecal microbiota, and also caused more efficient carbohydrate utilization for energy expenditure. Conclusion: YB resulted in body weight loss, promoted lipid catabolism and carbohydrate utilization; it also modulated cecal microbiota, and therefore partially improved the health of obese mice.
    關聯: FOOD & FUNCTION 卷: 6 期: 8 頁碼: 2727-2735
    显示于类别:[動物科學系 ] 期刊論文

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