A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana

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题名:	A novel cytotoxic C-methylated biflavone, taiwanhomoflavone-B from the twigs of Cephalotaxus wilsoniana
作者:	Kuo Y.H. Hwang S.Y. Kuo LMY Lee Y.L. Li S.Y. Shen Y.C.
贡献者:	化學系
关键词:	Cephalotaxus wilsoniana cytotoxicity taiwanhomoflavone-B;7,4 ',7 ''-tri-O-methylamentoflavone 6-C-methyl-naringenin kamepferol apigen-7-O-beta-glucoside
日期:	2002
上传时间:	2009-12-04 14:39:27 (UTC+8)
摘要:	A novel C-methylated biflavone, taiwanhomoflavone-B (1), together with known compounds, 7,4',7-tri-O-methylamentollavone, 6-C-methyinaringenin and apigenin-7-O-beta-glucoside were isolated from an ethanolic extract of Cephalotaxus wilsoniana. The structure of 1 was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-B is cytotoxic with ED50, values of 3.8 and 3.5 mug/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively.
關聯:	CHEMICAL & PHARMACEUTICAL BULLETIN Volume: 50 Issue: 12 Pages: 1607-1608
显示于类别:	[化學系所] 期刊論文

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