文化大學機構典藏 CCUR:Item 987654321/29233
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    题名: Polymorphisms in the promoter region of myostatin gene are associated with carcass traits in pigs
    作者: Tu, P.-A.
    Lo, L.-L.
    Chen, Y.-C.
    Hsu, C.-C.
    Shiau, J.-W.
    Lin, E.-C.
    Lin, R.-S.
    Wang, P.-H.
    贡献者: 動物科學系
    关键词: Carcass trait
    marker assisted selection
    Myostatin (MSTN) gene
    polymorphism
    porcine
    日期: 2014-04
    上传时间: 2015-01-27 11:35:04 (UTC+8)
    摘要: Higher average daily gain, more lean meat yield and less fat yield of porcine carcass increase selling profits for animal producers. Myostatin (MSTN), previously called GDF8, is a member of transforming growth factor- (TGF-) superfamily. It is a negative regulator for both embryonic development and adult homeostasis of skeletal muscle. In this study, the genotypes of the previously described SNPs MSTN g.435G>A and g.447A>G SNPs in 66 Duroc pigs, 33 Landrace pigs, 180 DurocxLandrace (DL) pigs and 155 DurocxYorkshirexLandrace (DYL) pigs were determined by Taqman SNP Genotyping Assays. For Duroc and Landrace pigs, MSTN g.435GG/g.447AA individual had greater backfat thickness (p<0.05) than g.435AA/g.447GG individual, whereas MSTN g.435AA/g.447GG had greater meat (p<0.05) and meat percentage (p<0.05) than g.435GA/g.447AG individual. For DL and DYL pigs, the MSTN g.435GG/g.447AA animals were greater in backfat at ultrasound 10th rib (p<0.05) and carcass 10th rib (p<0.01) than g.435AA/g.447GG individual. The MSTN g.435AA/g.447GG individual also had higher values than g.435GG/g.447AA for anterior-end meat (p<0.05), posterior-end meat (p<0.01), total meat weight (p<0.01) and meat percentage (p<0.01). This study confirmed evidence that MSTN g.435G>A and g.447A>G affected carcass traits in pigs. The effects of the mutated alleles were additive with the maximal effects resulting from two copies of the mutated allele. Selection for MSTN g.435A/g.447G allele is expected to increase muscle of limb and total meat production and decrease backfat thickness.
    關聯: JOURNAL OF ANIMAL BREEDING AND GENETICS 卷: 131 期: 2 頁碼: 116-122
    显示于类别:[動物科學系 ] 期刊論文

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