牛樟芝萃取物對於α-葡萄糖苷酶抑制活性的探討

文化大學機構典藏 CCUR > 環境規劃暨生物資源學院 > 農學院 > 生物科技研究所 > 博碩士論文 > Item 987654321/28242

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://irlib.pccu.edu.tw/handle/987654321/28242

题名:	牛樟芝萃取物對於α-葡萄糖苷酶抑制活性的探討 α-Glucosidase inhibitory effect by the extract ofAntrodia cinnamomea
作者:	詹孟翰
贡献者:	生物科技研究所
关键词:	α-葡萄糖苷酶抑制劑牛樟芝 α-glucosidase inhibitor Antrodia cinnamomea
日期:	2014
上传时间:	2014-09-26 15:39:27 (UTC+8)
摘要:	流行病學研究指出，關於糖尿病血糖平衡有兩大指標，一為空腹血糖，另外一個為飯後血糖，其中控制飯後血糖更為重要，α-葡萄糖苷酶抑制劑具有有效降低飯後血糖之效果，但服用α-葡萄糖苷酶抑制劑降血糖藥後常會發生腸胃不適的症狀，除此更有研究指出合成α-葡萄糖苷酶抑制劑可能會增加腎臟腫瘤、嚴重肝損傷及急性肝炎的發生率。牛樟芝具有許多的有效成分具有抗肝癌、血癌與胰臟癌增加免疫能力、抗過敏、降血壓、降血糖的效果經由本研究結果指出牛樟芝發酵液以及牛樟芝菌絲體抑制α-葡萄糖苷酶活性的IC50分別為318以及380mg/ml的抑制效果，發酵液的抑制效果高於菌絲體，可以作為α-葡萄糖苷酶抑制劑。 Epidemiological studies indicate that diabetes two indicators on blood sugar balance , one is fasting glucose, another is postprandial glucose level. Postprandial glucose level is more important to control blood sugar after a meal, when α-glucosidase inhibitors would reduce its effect. Taking the α-glucosidase inhibitors to manage blood glucose level result in hypoglycemic symptoms of gastrointestinal discomfort,and many studies have pointed out the synthestic of α-glucosidase inhibitors may would increase kidney tumors, severe liver injury and the occurrence of acute hepatitis rate. Antrodia was known of many active ingredients with anti-cancer, leukemia and pancreatic cancer, increased immunity, allergy, and blood pressure, and blood glucose lowering effect. According to the results of this study indicate Antrodia broth and mycelium of Antrodia show respectively 318 and 380 mg/ml inhibitory effect. On α-glucosidase activity and the inhibitory effect of the fermented liquid is how even higher than that of the mycelium, compared to other naturak herbs.excessive doses needed who found in Antroidia, it is less suitable an excellent α-glucosidase inhibitor than connent found onto.
显示于类别:	[生物科技研究所 ] 博碩士論文

文件中的档案:

没有与此文件相关的档案.

检视Licence

在CCUR中所有的数据项都受到原著作权保护.

数据加载中.....