Title: | Isolation, structure elucidation, and syntheses of isoneocryptotanshinone II and tanshinlactone a from Salvia miltiorrhiza |
Authors: | Sun CM;Chin TM;Lin YL;Chen CJ;Chen WC;Wu TS;Don MJ |
Contributors: | 化學系 |
Date: | 2006 |
Issue Date: | 2009-11-20 15:09:00 (UTC+8) |
Abstract: | Two new components, isoneocryptotanshinone II (1) and tanshinlactone A (2), were isolated from an EtOH extract of Salvia miltiorrhiza. The structures of I and 2 were established by spectroscopic methods and total syntheses. Compound (2) exhibited moderate cytotoxic activities with a CD50 range of 6.87-8.85 mu g/mL against the HeLa (cervical epithelold carcinoma), HepG2 (hepatocellular carcinoma) and OVCAR-3 (ovarian adenocarcinoma) cell lines |
Relation: | HETEROCYCLES Volume: 68 Issue: 2 Pages: 247-255 |
Appears in Collections: | [Department of Chemistry & Graduate Institute of Applied Chemistry ] journal articles
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