本研究旨在探討跑前連續7天補充輔酶Q10對超級馬拉松跑後自由基之影響。研究對象為有長跑習慣之男性9名，年齡 50.5 ± 10.47歲、身高168.5 ± 6.0公分、體重 63.1 ± 6.74公斤、跑齡 8.5 ± 4.79年。研究設計採平衡次序（balanced order）重覆量數法，將9名跑者分成兩組，分別參加二次練習跑。第一次練習跑為跑前七天連續補充輔酶Q10（100 mg）組；一為跑前七天連續補充安慰劑P（麥芽糊精）組，於第二次練習跑時兩組所補充之增補劑互換，屬雙盲實驗。9名跑者於 6-8 小時間平均完成 57.5 ±11.6公里，二次練習跑環境平均溫度16.78 ± 0.98 ℃、濕度 92.63 ± 3.35％，跑步期間允許自由飲食，在跑前30分鐘及跑後即刻採集血液進行生化值之分析，觀察其超氧化歧化酶（SOD）活性及麩胱甘肽過氧化酶（GSH-Px）濃度及丙二醛（MDA）變化情形。以相依樣本成對樣本t檢定（t - test）進行考驗，顯著差異水準α＝.05。結果為跑者不論是Q組或是P組的MDA、GSH-Px、SOD跑前、跑後均無顯著差異（p >.05）。本研究之結論是補充輔酶Q10對超級馬拉松跑後之內自由基並無顯著影響。
The purpose of this study was to investigate the effect of the free radical in post ultra marathon period to a 24 hours ultra marathon’s runner with supplying Coenzyme Q10 for 7 days before ultra marathon period. Subjects are 9 males who used to run long distance regularly with mean age of 50.5±10.47 yr, height of 168.5±6.0cm, weight of 63.1±6.74kg, and experience in running age of 8.5±4.79. Research design took balanced order as the research method, the study was divided 9 male runners into two groups and each participated practicing for twice. First practicing run was in supplying Coenzyme Q10 (100mg) for 7days before ultra marathon period group; another was in supplying placebo for 7days before ultra marathon period group, as for second practicing run, the supplements which supplied for these two groups will be exchanged, it’s the double blind experiment. 9 runners completed 57.5±116.km equally in 6-8 hours; the environment average temperature of the second practicing run is 16.78±0.98℃, the humidity 92.63±3.35％, It is allowed to dining during running, the blood sampling were collected instantly after and before 30 minutes running to analyze the biochemistry evaluation , and then observes the change of SOD, GSH-Px and MDA. These data by using t-test to processed with α＝.05. The result indicated that whether Q group or P group, there was no significant effect of MDA, GSH-Px, and SOD and after run and before run. In conclusion, it has no a significant effect of the free radical in supplying Coenzyme Q10 to 24 hours ultra marathon runners.
