| Title: | Large-scale synthesis of per-O-acetylated saccharides and their sequential transformation to glycosyl bromides and thioglycosides |
| Authors: | Lin, Chang-Ching
Huang, Li-Cheng
Liang, Pi-Hui
Liu, Ching-Yang
Lin, Chun-Cheng |
| Contributors: | 化學系 |
| Keywords: | acetylation
LiClO4
one-pot synthesis
glycosyl bromides
thioglycosides |
| Date: | 2006 |
| Issue Date: | 2009-11-20 13:25:03 (UTC+8) |
| Abstract: | This work describes a large-scale synthesis of per-O-acetylated mono- and disaccharides using a stoichiometric amount of acetic anhydride in the presence of LiClO4 under solvent-free conditions. The peracetylated saccharides underwent subsequent anomeric bromination and thioglycosidation in one-pot to yield synthetically valuable building blocks. |
| Relation: | JOURNAL OF CARBOHYDRATE CHEMISTRY Volume: 25 Issue: 4 Pages: 303-313 |
| Appears in Collections: | [化學系所] 期刊論文
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