This study examines complexity in expatriate adjustment, both its antecedents and consequences. As the prior studies about expatriate’s adjustment have explained that family, individual and organizational factors are all significantly related to expatriate adjustment, but these studies do not integrate the antecedents and consequences of expatriate adjustment into and more comprehensive research model. Therefore, a research framework is proposed that integrates the expatriate adjustment into various theoretical construct such as innovative work behavior, expatriate performance, and also knowledge transfer. A meta-analytic review is adopted in this study. The 102 studies related with expatriate adjustment state that family factors, individual factors and organizational factors all have significant influences on expatriate adjustment. Furthermore, expatriate adjustment further influence expatriate innovative behavior, expatriate performance and knowledge transfer.