| 摘要: | 臺灣黃蘗(Phellodendron amurense)又名黃柏、川柏，為芸香科黃蘗屬之植物，臺灣特有變種(Endemic variety)。富含生物鹼類，其中主要成份小蘗鹼(berberine)在體外試驗對於金黃色葡萄球菌、肺炎球菌；白喉桿菌、草綠色鏈球菌、痢疾桿菌等均有抗菌作用。台灣黃蘗依其地理及海拔分布，其小蘗鹼含量從2.1%到3.1%，可知顯現出種源變異，由於藥用市場的需求，台灣黃蘗近年來遭非法砍伐或剝皮屢有所聞，導致原始林內臺灣黃蘗族群量大減，農委會將它列為瀕臨滅絕的等級。由於黃蘗不論在中、西醫皆是非常重要藥材，臺灣黃蘗二次代謝物含量又優於其他國家，在目前山坡地超限利用嚴重，林業木材減低伐量，森林藥用植物市場研發開拓將可帶來嶄新的契機。本研究希望以98年度種源調查為依據，分別進行採種、成份分析、無性繁殖、建立種原平台。進一步以採取枝條、樹皮、組織培養為材料，進行臺灣黃蘗二次代謝物萃取，並作抗潰瘍作用的試驗研究。
Phellodendron amurense also names the cork, the Sichuan cypress, Taiwan unique variety (Endemic variety).Contains the biological alkalis richly, in which essential component berberine in vitro experiment regarding the golden yellow staphylococcus, the pneumococcus; Diphtheria bacillus, the streptococcus viridans, the shigella and so on has the resist bacteria function. Phellodendron amurense according to its geography and the elevation distribution, its bererine content from 2.1% to 3.1%, may know appears the seedling source variation, as a result of the for medicinal purposes market demand, Phellodendron amurense suffered the illegal felling in recent years or bark has repeatedly heard, caused in the natural forest group quantity to reduce greatly, the council of agricultural could list as bordered on extinguishes. Because Phellodendron amurense no matter in, the doctor practicing western medicine all is the extremely important raw material for medicine, the secondary metabolite content surpasses other countries, ultra limits the use in the present hilly land to be serious, the forestry lumber will decrease cuts down the quantity, the forest medicinal plant market research and development may bring the new turning point. This research hope take 98 year seedling source investigation as the basis, carries on the seed collecting, the ingredient analysis, the vegetative reproduction, the establishment separately plants the original platform. Further take adopts the branch, the bark, the tissue culture as the material, carries on the secondary metabolite extract, and makes the anti-ulcer function the experimental study. |
