In this study, Chinese medicine Gardenia was found to prepare a natural gelatin cross linking agent. It replaced the toxic chemistry complex, such as glutaraldehyde and formaldehyde, which were often used in other studies. The gelatin microcapsule was prep rated by Simple coacervation method that was observed by the shape, cross linking and controlled release. The result found the microcapsule gabled oil used. By the Fourier transform infrared analysis, all the reaction showed cross linking under the different concentrations. When concentration was higher, the function of cross linking had more base amides content. The particle size, 500.28±3.76μm, had better forming under the 500rpm rotational speed. Besides, the cross linking agent preparation in the acidic environment had better results when its reaction joined the gelatin of pH=4.0 and pH=5.5. On the other hand, the gelatin showed decreasing reactions on the surface at the Gelatin of pH=7. At the preparation, the Gardenia Fructose in the ethanol solution and the gelatin microcapsule are ratio under 1:3 condition, and it formed good shape under 30% concentrations. During the Fourier transform infrared analysis, the controlled release rate of the oil was found at the 17%. Furthermore, the controlled release rate was changed to 2%.
